Correlation of Insulin Resistance with Vitamin D, Ferritin, and TSH Levels

Noura Madi; Ali Elassawi; Ezelarab Ahwedg

doi:10.33214/zg2n8b72

Authors

Noura Madi Department of Clinical Nutrition, Faculty of Medical Technology, Misrata, Libya Author
Ali Elassawi Department of Clinical Nutrition, Faculty of Medical Technology, Misrata, Libya. Author
Ezelarab Ahwedg Department of Clinical Nutrition, Faculty of Medical Technology, Misrata, Libya. Author

DOI:

https://doi.org/10.33214/zg2n8b72

Keywords:

Insulin Resistance, Vitamin D, Ferritin, TSH.

Abstract

Insulin resistance (IR) is a key component of metabolic disorders such as type 2 diabetes, obesity, and cardiovascular disease. This cross-sectional study aimed to investigate the relationship between insulin resistance and three biochemical markers: vitamin D, ferritin, and thyroid-stimulating hormone (TSH). 67 participants (39 females, 28 males) were assessed from Misrata, Libya. Insulin resistance was estimated using the Homeostasis Model Assessment (HOMA-IR). The study found a high prevalence of significant insulin resistance among participants, particularly among females. Pearson correlation analysis revealed a moderate positive correlation between TSH and HOMA-IR and a negative correlation between vitamin D and HOMA-IR, while no significant associations were observed with ferritin or age. The findings highlight the potential role of vitamin D deficiency and thyroid function in insulin resistance. These results support the importance of including vitamin D and TSH screening in routine metabolic assessments, especially for populations at risk.

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